Vitamin D is a hormone of steroid origin which is responsible for enhancing the calcium absorption by the intestines and the regulation of its homeostasis. There are two most common forms Vit. D: Vitamin D2 and Vitamin D3. Vitamin D3 is produced naturally in the skin by the exposure to ultraviolet light. The Vitamin D2 is mostly obtained through food intake. Vitamin D is metabolized to 25hydroxy Vitamin D the liver. A 25-hydroxy Vitamin D blood test is used by the medics to determine the concentration of Vitamin D in the patient’s body. The blood concentration of 25-hydroxy Vitamin D (including D2 and D3) is considered the best indicator of Vitamin D status.
Vitamin D deficiency has now been recognised as an epidemic of global magnitude. Almost every cell in the human body has receptors for Vitamin D. This means that they all of them require a certain level of Vitamin D for maintaining their functions and viability. As more studies were done and more data accumulated, it became clear that the health risks associated with Vitamin D deficiency are much more severe than the ones previously suspected. Vitamin D deficiency is associated to a number of serious diseases such as Osteoporosis, Osteomalacia, Multiple Sclerosis, Cardiovascular Diseases, Pregnancy Complications, Diabetes, Depression, Strokes, Autoimmune Diseases, Flu, Different Cancers, Infectious Diseases, Alzheimer, Obesity and Higher Mortality, etc. Due to this nowadays the detection of (25-OH) Vitamin D levels is embraced by the medical community as “Medically Necessary Screening Test”. Now it is well understood that maintaining sufficient levels of Vit. D isn’t just necessary for improvement of bone health, but is also essential for the overall health and well-being of the individuals.
Though multiple studies on Vitamin D deficiency have been performed and published by a number of health organizations, a common and accepted by all recommendation for the levels of Vit. D still remains to be established. Based on recent studies and literature the following table of ranges for the classification of Vitamin D is suggested:
|25-OH Vitamin D Level
||Reference Range (ng/ml)
||0 – 10
||10 – 30
||30 – 100